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KMID : 0903520040470020279
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Journal of the Korean Society of Agricultural Chemistry and Biotechnology
2004 Volume.47 No. 2 p.279 ~ p.282
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An Antioxidant Homo-Flavoyadorinin-B from Korean Mistletoe (Viscum album var. coloratum)
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Choi Seung-Young
Chung Shin-Kyo
Kim Suk-Kyung
Yoo Young-Choon
Lee Kyung-Bok
Kim Jong-Bae
Kim Ja-Young
Song Kyung-Sik
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Abstract
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An antioxidant was isolated from Korean mistletoe (Viscum album var. coloratum) by consecutive purification using silica gel, Sephadex LH-20, and RP-HPLC. The active principle was identified as homoflavoyadorinin- B (3’,7-dimethoxyluteolin-4’-O-[apiosyl (12) glucoside]) by spectral analyses. It inhibited 74.6% of hydroxyl radical and 30.6% of superoxide anion radical at 0.01 mM; however, the compound did not show any scavenging activity against hydrogen peroxide radical. At 0.1 mM, above compound scavenged superoxide anion radical about twice as effective as positive controls, BHT and α-tocopherol. Radical scavenging activities of homoflavoyadorinin- B on DPPH, hydroxyl, and hydrogen peroxide radicals were almost same with those of positive controls.
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KEYWORD
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Viscum album var, coloratum, reactive oxygen species scavenger, antioxidant, homo-flavoyadorinin-B
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